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Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia
2.682
Zitationen
30
Autoren
2020
Jahr
Abstract
In previously untreated patients who were ineligible for intensive chemotherapy, overall survival was longer and the incidence of remission was higher among patients who received azacitidine plus venetoclax than among those who received azacitidine alone. The incidence of febrile neutropenia was higher in the venetoclax-azacitidine group than in the control group. (Funded by AbbVie and Genentech; VIALE-A ClinicalTrials.gov number, NCT02993523.).
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Autoren
- Courtney D. DiNardo
- Brian A. Jonas
- Vinod Pullarkat
- Michael J. Thirman
- Jacqueline S. Garcia
- Andrew H. Wei
- Marina Konopleva
- Hartmut Döhner
- Anthony Letai
- Pierre Fenaux
- Elizabeth A. Koller
- Violaine Havelange
- Brian Leber
- Jordi Esteve
- Jianxiang Wang
- Vlatko Pejša
- Roman Hájek
- Kimmo Porkka
- Árpád Illés
- David Lavie
- Roberto M. Lemoli
- Kazuhito Yamamoto
- Sung‐Soo Yoon
- Jun‐Ho Jang
- Su‐Peng Yeh
- Mehmet Turgut
- Wan‐Jen Hong
- Ying Zhou
- Jalaja Potluri
- Keith W. Pratz
Institutionen
- The University of Texas MD Anderson Cancer Center(US)
- University of California, Davis(US)
- City of Hope(US)
- University of Chicago(US)
- Dana-Farber Cancer Institute(US)
- Harvard University(US)
- Monash University(AU)
- University Hospital Ulm(DE)
- Assistance Publique – Hôpitaux de Paris(FR)
- Université Paris Cité(FR)
- Hanusch Hospital(AT)
- Cliniques Universitaires Saint-Luc(BE)
- McMaster University(CA)
- Biomedical Research Institute(US)
- Institute of Hematology & Blood Diseases Hospital(CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College(CN)
- University Hospital Dubrava(HR)
- University of Zagreb(HR)
- University Hospital Ostrava(CZ)
- Helsinki University Hospital(FI)
- University of Helsinki(FI)
- Hadassah Medical Center(IL)
- University of Genoa(IT)
- Ospedale Policlinico San Martino(IT)
- Aichi Cancer Center(JP)
- New Generation University College(ET)
- Seoul National University(KR)
- Sungkyunkwan University(KR)
- Samsung Medical Center(KR)
- China Medical University Hospital(TW)
- China Medical University(TW)
- Ondokuz Mayıs University(TR)
- AbbVie (United States)(US)
- University of Pennsylvania(US)