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A systematic review of ethical considerations of large language models in healthcare and medicine

2025·15 Zitationen·Frontiers in Digital HealthOpen Access
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15

Zitationen

5

Autoren

2025

Jahr

Abstract

, 51.8%) among examined models. While privacy protection and bias mitigation received notable attention in the literature, no existing review has systematically addressed the comprehensive ethical issues surrounding LLMs. Most previous studies focus narrowly on specific clinical subdomains and lack a comprehensive methodology. As a systematic mapping of open-access literature, this synthesis identifies dominant ethical patterns, but it is not exhaustive of all ethical work on LLMs in healthcare. We also synthesize identified challenges, outline future research directions and include a provisional ethical integration framework to guide clinicians, developers, and policymakers in the responsible integration of LLMs into clinical workflows.

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