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Pathologist-like explainable AI for interpretable Gleason grading in prostate cancer
2025·6 Zitationen·Nature CommunicationsOpen Access
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Zitationen
67
Autoren
2025
Jahr
Abstract
) while providing interpretable outputs. We release this dataset to encourage further research on segmentation in medical tasks with high subjectivity and to deepen insights into pathologists' reasoning.
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Autoren
- Gesa Mittmann
- Sara Laiouar-Pedari
- Hendrik A. Mehrtens
- Sarah Haggenmüller
- Tabea-Clara Bucher
- Tirtha Chanda
- Nadine T. Gaisa
- Mathias Wagner
- Gilbert Georg Klamminger
- Tilman T. Rau
- Christina Neppl
- Éva Compérat
- Andreas Gocht
- Monika Haemmerle
- Niels J. Rupp
- Jula Westhoff
- Irene Krücken
- Maximilian Seidl
- Christian M. Schürch
- Marcus Bauer
- Wiebke Solaß
- Yu Chun Tam
- Florian Weber
- Rainer Grobholz
- Jaroslaw Augustyniak
- Thomas Kalinski
- Christian Hörner
- Kirsten D. Mertz
- Constanze Döring
- Andreas Erbersdobler
- Gabriele Deubler
- Felix Bremmer
- Ulrich Sommer
- Michael Brodhun
- Jon Griffin
- Maria Sarah L. Lenon
- Kiril Trpkov
- Liang Cheng
- Fei Chen
- Angelique Levi
- Guoping Cai
- Tri Q. Nguyen
- Ali Amin
- Alessia Cimadamore
- Ahmed Shabaik
- Varsha Manucha
- Nazeel Ahmad
- Nidia Messias
- Francesca Sanguedolce
- Diana Taheri
- Ezra Baraban
- Liwei Jia
- Rajal B. Shah
- Farshid Siadat
- Nicole Swarbrick
- Kyung Park
- Oudai Hassan
- Siamak Sakhaie
- Michelle R. Downes
- Hiroshi Miyamoto
- Sean R. Williamson
- Tim Holland‐Letz
- Christoph Wies
- Carolin V. Schneider
- Jakob Nikolas Kather
- Yuri Tolkach
- Titus J. Brinker
Institutionen
- German Cancer Research Center(DE)
- Heidelberg University(DE)
- University Hospital Heidelberg(DE)
- Universität Ulm(DE)
- University Hospital Ulm(DE)
- RWTH Aachen University(DE)
- Saarland University(DE)
- Düsseldorf University Hospital(DE)
- Heinrich Heine University Düsseldorf(DE)
- Medical University of Vienna(AT)
- University Hospital Schleswig-Holstein(DE)
- University of Lübeck(DE)
- Martin Luther University Halle-Wittenberg(DE)
- University of Zurich(CH)
- University Hospital of Zurich(CH)
- Städtisches Klinikum Karlsruhe(DE)
- Klinikum Bremen-Mitte(DE)
- University of Tübingen(DE)
- University of Bern(CH)
- Technische Hochschule Georg Agricola(DE)
- Ruhr University Bochum(DE)
- University of Regensburg(DE)
- Kantonsspital Aarau(CH)
- Schwyz University of Teacher Education(CH)
- Universitätsklinikum Brandenburg an der Havel(DE)
- University of Mannheim(DE)
- University Medical Centre Mannheim(DE)
- University Hospital of Basel(CH)
- Department of Biomedicine Basel(CH)
- Westsächsische Hochschule Zwickau(DE)
- University of Rostock(DE)
- Kreiskliniken Reutlingen(DE)
- Helios Klinikum Erfurt(DE)
- University of Sheffield(GB)
- University of Santo Tomas Hospital(PH)
- National Kidney and Transplant Institute(PH)
- Rockyview General Hospital(CA)
- Brown University(US)
- NYU Langone Health(US)
- Yale University(US)
- University Medical Center Utrecht(NL)
- University of Udine(IT)
- University of California San Diego(US)
- Jackson Memorial Hospital(US)
- University of Mississippi Medical Center(US)
- James A. Haley Veterans' Hospital(US)
- Washington University in St. Louis(US)
- University of Foggia(IT)
- Isfahan University of Medical Sciences(IR)
- Tehran University of Medical Sciences(IR)
- Johns Hopkins University(US)
- The University of Texas Southwestern Medical Center(US)
- Pathwest Laboratory Medicine(AU)
- Henry Ford Health System(US)
- Frankston Hospital(AU)
- Sunnybrook Health Science Centre(CA)
- Health Sciences Centre(CA)
- University of Rochester Medical Center(US)
- Cleveland Clinic(US)
- Universitätsklinikum Aachen(DE)
- University of Leeds(GB)
- National Center for Tumor Diseases(DE)
- University Hospital Carl Gustav Carus(DE)
- University of Cologne(DE)
- University Hospital Cologne(DE)
Themen
AI in cancer detectionRadiomics and Machine Learning in Medical ImagingArtificial Intelligence in Healthcare and Education